EyeWorld Weekly, January 29, 2021

➤ Topline results from Phase 3 studies for nAMD treatment ➤ Phase 2 trial of betamethasone treatment for cataract surgery pain and inflammation ➤ Fast Track designation given to therapy seeking to treat achromatopsia ➤ Topline data from Phase 1 trial of travoprost intracameral implant ➤ ASCRS Journal Club

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EyeWorld Weekly, January 22, 2021

➤ Enrollment complete for Phase 3 studies of investigational dry eye drug ➤ Update from two Glaukos trials ➤ Study: Remote monitoring with implantable IOP sensor affects clinical decision making ➤ ASCRS events

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EyeWorld Weekly, January 15, 2021

➤ Success with first-in-human implant of new artificial cornea ➤ Launch of first longitudinal study for home OCT ➤ Enrollment complete for study evaluating treatment for Leber congenital amaurosis 10 ➤ Phase 1/2a trial for wet AMD treatment with suprachoroidal injection begins enrollment ➤ Fast Track designation issued for investigational dry AMD therapy

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Dry eye during the COVID-19 pandemic

With the COVID-19 pandemic temporarily closing practices around the country, many ophthalmologists had to figure out how to still communicate with and treat their patients. Several physicians commented on how the pandemic has affected their dry eye patient population and trends they have seen.

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Real-world treatment patterns of two dry eye drugs

A retrospective study based on insurance claims data is giving real-world insights into prescribing/treatment patterns for two dry eye medications—cyclosporine ophthalmic emulsion (Restasis, Allergan) and lifitegrast ophthalmic solution (Xiidra, Novartis).1 In doing so, researchers can make inferences on adherence, discontinuation, and more.

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How the latest trends may be affecting the ocular surface in teens
This 20-year-old college student with meibomian gland dropout and lid seal insufficiency had dry eye complaints. The student reported long computer hours, poor sleep, poor nutrition, excessive contact lens wear, and use of multiple over-the-counter and prescription acne treatment products. Source: Laura Periman, MD

How the latest trends may be affecting the ocular surface in teens

When teens come into the clinic, it’s important to consider that they might have dry eye or meibomian gland disease. Investigators in a recent study found that among minors coming in for eye exams, 15% were experiencing dry eye discomfort and 9% had signs of meibomian gland dropout, according to lead investigator Anna Tichenor, PhD.1

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COVID-19 and its impact on eye banking

The COVID-19 pandemic has affected all areas of medicine, including eye banking. While much more is known about SARS-CoV-2 and the illness it causes, there are still several unknowns that continue to be investigated as they pertain to the safety of donor tissue.

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Xiidra out of the comfort zone

any practitioners are now reaching for Xiidra (lifitegrast, Shire, Lexington, Massachusetts) 5% for dry eye cases, but sometimes a patient may not initially be considered a success. Here’s what leading practitioners are doing to help more patients find respite with Xiidra.

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